Tracking the relevant researches of CADD drug development against COVID-19
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (By similarity). May modulate transforming growth factor-beta signaling by binding host smad3 (By similarity). [Uniprot]
Chain A: N49 T50 A51 S52 F54 T55 A56 R89 R90 A91 T92 R93 R94 I95 L105 R108 Y110 Y112 P118 G130 T149 R150 N151 P152 A153 A156 A157 A174
Chain A: W53 F54 P74 I75 N76 T77 N78 S79 S80 P81 D83 Q84 F111 Y112 Y113 H146 I147 G148 T149 N154 N155 A156 A157 I158 V159 L160 Q161
Chain A: R69 G70 Q71 V73 P74 I75 N76 T77 S79 S80 P81 D82 Q84 A135 T136 E137 G138 A139 L162 P163 Q164 G165 T166
Chain A: Q59 K62 E63 D64 L65 K66 F67 P68 R69 Q71 R90 W109 Y124 G125 A126 N127 K128 D129 G130 I131 I132 W133 V134 A135 T167 P169 K170 F172