Tracking the relevant researches of CADD drug development against COVID-19
Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages. [DrugBank]
Voltage-dependent L-type calcium channel (Humans); Voltage-dependent T-type calcium channel (Humans) [DrugBank]
Manidipine produces vasodilation resulting in lower blood pressure 1. [DrugBank]
Tips: Click on the link to jump to the 'SwissTargetPrediction' webserver. Select the species of 'Homo sapiens', and then paste the SMILES of Manidipine in the SMILES input box.
Tips: Click on the link to jump to the 'CB-Dock' webserver. Upload the structure file of target predicted by 'SwissTargetPrediction' and the 2D/3D structure file of Manidipine to perform blind docking.