Cavity detection
Structure-based cavity detection (Submitted Protein: MDM2.pdb)

Tips: Click the table below to view the pocket information. Click the residue in the sequence list to view the residue you are interested in.

Query 
A
.
Q
.
I
20
P
.
A
.
S
.
E
.
Q
.
E
.
T
.
L
.
V
.
R
30
P
.
K
.
P
.
L
.
L
.
L
.
K
.
L
.
L
.
K
40
S
.
V
.
G
.
A
.
Q
.
K
.
D
.
T
.
Y
.
T
50
M
.
K
.
E
.
V
.
L
.
F
.
Y
.
L
.
G
.
Q
60
Y
.
I
.
M
.
T
.
K
.
R
.
L
.
Y
.
D
.
A
70
A
.
Q
.
Q
.
H
.
I
.
V
.
Y
.
C
.
S
.
N
80
D
.
L
.
L
.
G
.
D
.
L
.
F
.
G
.
V
.
P
90
S
.
F
.
S
.
V
.
K
.
E
.
H
.
R
.
K
.
I
100
Y
.
T
.
M
.
I
.
Y
.
R
.
N
.
L
.
V
CurPocket
ID		 Cavity
volume (Å3)		 Center
(x, y, z)		 Cavity size
(x, y, z)
C1543-25, 8, -1210, 21, 10
C258-29, 12, -34, 8, 5
C333-11, 26, -43, 4, 5
C431-10, 11, -34, 4, 3
C526-15, 20, 15, 2, 4
Blind Docking
Detected cavities and predicted ligand-binding poses
Submitted Protein
MDM2.pdb
Submitted Ligand
Nutlin-3a.sdf
Detected Pockets
5
Representative binding poses
5
Structure-based blind docking
Submitted Protein
MDM2.pdb
Submitted Ligand
Nutlin-3a.sdf
Detected CurPockets
5
Template-based blind docking
Submitted Protein
MDM2.pdb
Submitted Ligand
Nutlin-3a.sdf
Detected FitPockets
1
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